Research

• 頭痛與疼痛

  Cellular Mechanisms Underlying Central Sensitization in a Mouse Model of Chronic Muscle Pain

  Yu-Ling Lin, Zhu-Sen Yang, Wai-Yi Wong, Shih-Che Lin, Shuu-Jiun Wang, Shih-Pin Chen, Jen-Kun Cheng, Hui Lu, and Cheng-Chang Lien

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  Circulating MicroRNA Associated With Reversible Cerebral Vasoconstriction Syndrome

  Shih-Pin Chen, MD, PhD; Yi-An Chang, PhD; Chih-Hung Chou, PhD; Chi-Chang Juan, PhD; Hsin-Chen Lee, PhD; Luen-Kui Chen, PhD; Pei-Chun Wu, PhD; Yen-Feng Wang, MD, PhD; Jong-Ling Fuh, MD; Jiing-Feng Lirng, MD; Anne Ducros, MD, PhD; Hsien-Da Huang, PhD; Shuu-Jiun Wang, MD.

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  Pain sensitivities predict prophylactic treatment outcomes of flunarizine in chronic migraine patients: A prospective study

  Li-Ling Hope Pan, Yen-Feng Wang, Yu-Hsiang Ling, Kuan-Lin Lai, Shih-Pin Chen, Wei-Ta Chen, Rolf-Detlef Treede, Shuu-Jiun Wang

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  Machine Learning Based Classification and Prediction of Heat Pain Sensitivity using Resting-state EEG

  Fu-Jung Hsiao, Wei-Ta Chen, and Shuu-Jiun Wang

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  Resting-state occipital alpha power is associated with treatment outcome in patients with chronic migraine

  Li-Ling Hope Pan, Wei-Ta Chen, Yen-Feng Wang, Shih-Pin Chen, Kuan-Lin Lai, Hung-Yu Liu, Fu-Jung Hsiao*, Shuu-Jiun Wang*

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  Role of Neuronal NLRP3 inflammasome in cortical spreading depolarization-induced inflammatory response

  Pin-Yu Chen, Szu-Ting Chen, Tzu-Ting Liu, Shuu-Jiun Wang, Jiin-Cherng Yen, and Shih-Pin Chen

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  Long-term Menstrual Pain Modulates Brain Activities Underlying Vocal Emotion Perception

  Intan Low, Ian-Ting Chu, Wei-Chi Li, Hsiang-Tai Chao, Hong-Der Shen, Jen-Chuen Hsieh, and Li-Fen Chen

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  原發性痛經研究團隊近期重要研究成果

  謝仁俊、陳麗芬、趙湘台、黃貞瑜、劉盈丹、李瑋淇、劉競雄、李林鍵、徐培珊

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  Dynamic brainstem and somatosensory cortical excitability during migraine cycles

  Fu-Jung Hsiao, Wei-Ta Chen, Li-Ling Hope Pan, and Shuu-Jiun Wang

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• 發育與退化

  The Role of Plasma Biomarkers in Prodromal Stage of Dementia

  李宜蓉 Yi-Jung Lee, 陳廷斌 Ting-Bin Chen, 林思穎 Szu-Ying Lin

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  Efficient Generation of Functional Microglia-like Cells from Human Induced Pluripotent Stem Cells by Defined Transcription Factors

  Shih-Wei Chen, Shu-Cian Chen, Ming-Ji Fann and Yu-Hui Wong

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  Polysaccharides from Basella alba protect post-mitotic neurons against cell cycle reentry and apoptosis via suppression of sonic hedgehog expression induced by amyloid-beta peptide

  Ming-Hsuan Wu, Bo-Yu Hou, Ding-I Yang

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  Endoplasmic Reticulum stress induces of Alzheimer's disease-like phenotypes in the neuron derived from the induced pluripotent stem cell with D678H mutation on amyloid precursor protein

  Tania Devina, Yu-Hui Wong, Chiao Wan Hsiao, Irene Han-Juo Cheng

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  Genetic regulation of the developmental formation of corticostriatal circuits

  Wei-Chun Lee (李唯君), Shih-Yun Chen (陳仕昀), Bo-Han He (何柏翰), Yen-Hui Lee (李彦輝), Fu-Chin Liu (劉福清)

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  Effect of CEP85L deficiency during the corticogenesis

  Shih-Shun Hung*, Pei-Shan Hou

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  Efficiently Induced Human Retinal Ganglion-like Cells Provide a Platform for Studying the Optic Neuropathies

  Roxanne Hsiang-Chi Liou, Shih-Wei Chen, Hui-Chen Cheng, Pei-Chun Wu, An-Guor Wang, Ming-Ji Fann and Yu-Hui Wong

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  Molecular Mechanism of a Novel BAIAP2 Variant in the Pathogenesis of Lissencephaly

  Wan-Cian Lin, Meng-Han Tsai, Jin-Wu Tsai

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  Suppression of Transient Receptor Potential Ankyrin 1 Ameliorate Phagocytic Ability of Aβ in Astrocytes

  Hsuan-Yun Hu and Hsueh-Te Lee

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  運用跨領域方法研究神經發育與疾病之機轉

  黃嘉偉、林均儒、林芃慈、蘇彥霖、張芊惠

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  The role of DACH1 in human cortical development revealed by ESC-derived neural populations and cortical organoids

  Pei-Shan Hou and Hung-Chih Kuo

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  神經退化性疾病之轉譯醫學研究

  張奕晴, 徐語謙, 黃依如, 李晏嬅

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  The p53/NF-kappaB-dependent induction of sestrin2 by amyloid-beta peptides exerts antioxidative actions in neurons

  Yi-Heng Hsieh and Ding-I Yang

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  Molecular mechanism of novel FOXG1 variants in causing cortical malformations

  Tsai-Yu Lin, Haw-Yuan Cheng, Wang-Tso Lee, Lee-Chin Wong, Pei-Shan Hou, Jin-Wu Tsai

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  Genomic landscape of cerebral cavernous malformations: focusing on the CCM1, CCM2, CCM3 genes

  Jing-Hsiang Chang, Sanford P C Hsu, Chien-Chen Chou, Yen-Cheng Shih, Po-Tso Lin, Hsiang-Yu Yu, Cheng-Chia Lee, Hsin-Hung Chen, Jiing-Feng Lirng, Yo-Tsen Liu

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  Neuronal Intranuclear Inclusion Disease in Patients with Adult-onset Nonvascular Leukoencephalopathy

  Yi-Hong Liu, Yi-Chu Liao, and Yi-Chung Lee

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  YAP maintains the production of intermediate progenitor cells and upper-layer projection neurons in the mouse cerebral cortex

  Yi-Ching Su, Tzu-Heng Hung, Tzu-Fang Wang, Ying-Hsuan Lee, Tsu-Wei Wang, Jenn-Yah Yu

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• 精神

  An Amygdala-centered Hyper-connectivity Signature of Threatening Face Processing

  Yu-Chun Chen, Chenyi Chen, Yawei Cheng

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  Intermittent theta-burst stimulation ameliorates synaptic pathology in antidepressant-resistant depression rat model

  Chi-Wei Lee, Han-Fang Wu, Ming-Chia Chu, Yueh-Jung Chung, Cheng-Ta Li (李正達), Hui-Ching Lin (林惠菁)

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  The Long-Term Effects of Dextromethorphan on MDMA-Mediated Serotonergic Deficiency and Volumetric Changes in Primates Based on 4-[18F]-ADAM PET/MRI

  Skye Hsin-Hsien Yeh (葉信顯), Yu-Yeh Kuo (郭諭燁), Wen-Sheng Huang (黃文盛), Chuang-Hsin Chiu (邱創新), Tsung-Hsun Yu (游宗勳), Leo Garcia Flores II, Chi-Jung Tsai (蔡季蓉), Kuo-Hsing Ma (馬國興)

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  Antidepressant Efficacy of Intermittent Theta-Burst Stimulation is Similar to Low-Dose Ketamine & Mechanisms Involve BDNF

  Cheng-Ta Li, Chih-Ming Cheng, Mu-Hong Chen, Hui-Ching Lin, Hsin-Hsian Yeh, Ching-Po Lin, Tung-Ping Su

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  Machine Learning Approach to Modelling Trajectories of Decline in Brain Matter Volume, Cortical Thickness and White Matter Integrity Across Disease Course in Schizophrenia

  Jun-Ding Zhu, Shih-Jen Tsai, Albert C. Yang

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  Antidepressant Efficacy and Mechanisms of Newer Forms of Brain Stimulation

  Cheng-Ta Li, Hui-Ching Lin, Ching-Po Lin, Skyh-Hsien Yeh

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  Roles of Cardiovascular Autonomic Regulation and Sleep Pattern in Mild Cold Exposure-Induced High Blood Pressure in Rats

  Chieh-Wen Chen, Cheng-Han Wu, Yu-Syuan Liou, Kuan-Liang Kuo, Cheng-Hung Chung, Yu-Ting Lin, Terry B. J. Kuo, Cheryl C. H. Yang

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  Effects of Lactobacillus plantarum PS128 on Sleep and Physiological Parameters in Self-Reported Insomniacs: a Randomized-Controlled Trial

  Yu-Ting Ho, Ying-Chieh Tsai, Terry B. J. Kuo, Cheryl C. H. Yang

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  Is Schizophrenia a Disorder of Brain Network or Brain Hubs? A Functional Brain Connectome Analysis Using Functional Magnetic Resonance Imaging

  Yee-Lam E. Chan, M.D., Shih-Jen Tsai, M.D., Yi-Juang Chern, Ph.D., Albert C. Yang, M.D., Ph.D.

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• 認知

  The clinical relevance of serum BDNF level in Alzheimer disease and mild cognitive impairment patients

  蔡孟儒, MD, 林詠萱, MD, 陳俊宇, MD PhD, 傅中玲, MD

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  Brain reserve is associated with cognition in AD and MCI patients in different vascular risk factors status

  Wei-Ju Lee, MD, PhD, Ting-Bin Chen, MD, PhD, Hung-Chieh Chen, MD, Yu-Hsiu Yang, MS, Jong-Ling Fuh, MD

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  The FKBP51 and aryl hydrocarbon receptor (AhR) in inflammation and chronic disease-associated brain disorders

  李怡萱 (Yi-Hsuan Lee)

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  The association among plasma p-tau181, cognitive progression and structural brain change in early Alzheimer’s disease

  林詠萱, MD, 陳俊宇, MD PhD, 李威儒, MD PhD, 傅中玲, MD

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  Human orbitofrontal cortex represents the subjective value of the present, and the past food rewards

  Wan-Yu Shih, Hsiang-Yu Yu, Cheng-Chia Lee, Chien-Chen Chou, Chien Chen, Paul W. Glimcher, Shih-Wei Wu

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  A retrospective and stepwise learning strategy revealed by neuronal activity in the basal forebrain

  Hachi E. Manzur, Ksenia Vlasov, Shih-Chieh Lin

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  Over- and underreactions to regime shifts and their neurocomputational substrates

  Mu-Chen Wang, George Wu, Shih-Wei Wu

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  Altered functional connectivity induced by different music suites in heart-broken people

  Ling-Yao Chien and Wen-Jui Kuo

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  Context effects on visual perception and probability estimation

  Hui-Ching Hsu, Wan-Yu Shih, Shih-Wei Wu

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  Monetary gains and losses are represented by high-frequency oscillatory activity in the human brain

  Siao-Jhen Wu, Shih-Wei Wu

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• 神經技術

  Acceleration of Magnetic Resonance Fingerprinting Reconstruction Using Denoising and Self-Attention Pyramidal Convolutional Neural Network

  Jia-Sheng Hong, Ingo Hermann, Frank G. Zöllner, Lothar R. Schad, Shuu-Jiun Wang, Wei-Kai Lee, Yung-Lin Chen, Yu Chang, and Yu-Te Wu

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  Development of micropatterned biochip microscopic platform for early diagnosis of neurological diseases through exosomal detection of microRNA from liquid biopsies

  Yeh-Shiu Chu, Shih-Pin Chen, Xing-Yu Chen , Tai-Shan Cheng , Chi-Ying F. Huang , Chia Fu Chou, L. James Lee, Shuu-Jiun Wang

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  Exploring Peritumoral Neural Tracts by Using NODDI

  Shin Tai Chong, Xinrui Liu, Hung-Wen Kao, Chien-Yuan Eddy Lin, Chih-Chin Heather Hsu, Yi-Chia Kung, Kuan-Tsen Kuo, Chu-Chung Huang, Chun-Yi Zac Lo, Yunqian Li, Gang Zhao, Ching-Po Lin

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